COPD patients vary widely, due to their comorbidities, social circumstances, and wishes. So choosing the best treatment pathway for the patient can be complex. Involve senior decision makers.
Questions
- Is hospital the best place for them?
 - Do they need NIV?
 - Are they dying? – would you want to die surrounded by strangers or with your family?
 
Investigations – ALL if Admission
- Blood gases – Think VBG vs ABG
 - Chest X-ray
 - ECG
 - FBC/U&E + Theophylline level (if on theophylline).
 - Sputum microscopy and culture (if purulent sputum)
 - Blood Culture (if suspected sepsis)
 
Treatments
Will depend on the patient and severity of exacerbation
- Initial treatment for ALL: Neb. Controlled O2 and Steroids [<30mins]
 - Antibiotics [if purulent sputum]
 - Further treatment to Consider:
- Back to Back Nebs (Salbutamol and Ipratroprium)
 - IV Aminophylline
- 5mg/kg bolus (30min) upto 500mg (if not on theophylline)
 - Maintenance ONLY Aminophylline (post bolus / on theophylline)
 
 - NIV – persisting respiratory acidosis
 - Intubation?? (Often not suitable)
 
 
NIV – Guide HERE
Should be considered for all COPD patients with a persisting respiratory acidosis after a maximum of one hour of standard medical therapy
Discharge/Admission
This is frequently a difficult decision, with many medical and social influences. Information is key and utilise senior decision-making.

PDF:copd