Author: rebecca isles

Paediatric Mental Health

Paediatric Mental Health Concerns

The provision of out of hours mental health services for Children and young people (under the age of 18) and in hours services are different.

In-Hours (9am – 8pm) – contact CAMHS via switchboard

OOH (8pm – 9am) – contact the Mental Health Liason team (RAID) via switchboard (they will see/telephone review these patients initally and help with the mental health aspects including levels of risk and follow up plans with further mental health services)

Most, if not all, primary presentations to the ED with mental health concerns will meet the threshold for discussion with these services even if they decide same day review isn’t appropriate/they direct you elsewhere.

All self-harm and any overdose must be discussed!

Acute behavioural disturbance in children and young people has no nationally approved guideline and should be discussed with senior ED (ST4+), paediatric and mental health colleagues.

In young people for whom a HEADSSS assessment has been performed and you have low level concerns but for whom formal mental health/safeguarding thresholds have not been reached there are local resources which it may be useful to direct young people towards.

BLOSM colleagues are also a great resource repository even if children don’t meet formal referral criteria

Night OWLS – confidential emotional support line open between 8pm and 8am

Openminds Calderdale – repository of multiple sources of well-being support for children in Calderdale

Kirklees Keep in Mind – repository of multiple sources of well-being support for children in Kirklees

Minimal and Moderate Paediatric Sedation

The depth and type of sedation required in children depends on the procedure to be carried out. With the exception of procedures expected to cause pain most procedures in the Paediatric Emergency Department will not require pharmacological agents.

Painful procedures preformed for children in the ED are usually done with Ketamine Sedation for which there is a separate pathway – Ketamine Sedation

 

Minimal and Moderate Sedation

Minimal – Drug induced calm, the patient is awake and responds to verbal commands but may have impairment of cognition and coordination.

Moderate – Drug induced depression of consciousness but patients respond purposefully to verbal commands or tactile stimulation.

Prior to consideration of drugs for painless procedures please consider consider alternative strategies. There are playspecialists at both sites between 8am and 8pm most days! If play therapists aren’t available consider the use of favourite songs, distraction toys, and of course the modern day all-in-one fix of a phone/tablet with the child’s favourite show!

The help of an experienced nurse and capable parent cannot be underestimated. You should consider the use of intranasal fentanyl (see guideline) on presentation for more painful conditions, as well as paracetamol and ibuprofen.

You might diminish the pain on infiltration of (warmed) local anaesthetics by injecting slowly and using a fine gauge needle. If oral sedation is to be considered oral Chloral Hydrate or Buccal Midazolam should be considered, neither of these require cannulation.

Who can preform minimal/moderate sedation?

  • Senior medical staff (ST3+) with paediatric life support training
  • Must have done at least 6 months of anaesthetics/ICU
  • Familiar with giving medication of choice
  • Must have at least 2 staff members – someone to perform sedation, someone to monitor the patient
  • Department must be safe – Senior ED Clinician in charge (Consultant or Senior Registrar when Consultant not present in department has final say over if it is appropriate to perform at any given time

Benzodiazepine and chloral both have very variable effects in children and careful consideration of an alternative plan should be made. Can imaging be delayed until a play-therapist is present? Could they be bought into PAU for their imaging requirements? Can a specialist attend to clean and suture a wound under ketamine instead of just cleaning the wound and dressing?

Contraindications

Any of the following comorbidities / contraindications require discussion with an anaesthetist / senior paediatrician:

  • Abnormal airway – including large tonsils or craniofacial anomalies e.g. receding jaw, stiff neck, restricted mouth opening, very large head
  • Raised intra cranial pressure or depressed conscious level
  • History of obstructive sleep apnoea
  • Major organ dysfunction including congenital cardiac anomalies
  • Moderate to severe gastro oesophageal reflux disease
  • Neuromuscular disorders
  • Bowel obstruction
  • Intercurrent respiratory tract infection
  • Known allergy to sedative drug / previous adverse reaction
  • Multiple trauma
  • Refusal by parent / guardian / child
  • Corrected age < 1 year because of severe prematurity
  • ASA 3 or more

Fasting

  • For an emergency procedure in a child or young person who has not fasted, balance the risks and benefits of the decision to proceed with sedation before fasting criteria are achieved, on the urgency of the procedure and the target depth of sedation. Consider discussing this child with an anaesthetist.
  • Apply the 2-4-6 fasting rule for sedation in the ED unless child in significant distress and all other distraction and environmental alterations have been attempted.
    • 2 hours for clear fluids
    • 4 hours for breast milk
    • 6 hours for solids and formula milk

Medications

Chloral Hydrate

Oral – give 45-60 minutes before procedure, it has an unpleasant taste but can be mixed with blackcurrant squash

Dose: –

Minimal Sedation: 30-50 mg/kg Maximum 1g

Moderate Sedation: 100mg/kg Maximum 2g

Side Effects

Gastric irritation including nausea and vomiting reported.

Beware cardiac arrhythmias and respiratory depression with loss of airway reflexes at high doses.

There is NO reversal agent available

Buccal Midazolam

Buccal: Give 15 minutes pre-procedure and give half the dose into each side of the mouth

Dose: –

1-9 years:  0.2mg – 0.3mg/kg; Maximum 5mg

10-18 years:  6mg – 7mg; Maximum 8mg if 70kg or over

Side Effects

Short acting benzodiazepine causing sedation, hypnosis, anxiolysis, anterograde amnesia

Beware respiratory depression / hypotension / loss of airway reflexes at high doses.

Can lead to a distressing paradoxical excitement in children

Reversal agent: Flumazenil

Flumazenil dose: 10 microgram/kg [Max 200 microgram], repeat at 1 minute intervals up to 5 times.

 

Post sedation care

  • Observe for 1-2 hours until:
    • Conscious and responding appropriately
    • Able to walk unassisted (older children)
    • Vital signs are within normal limits
    • Respiratory status not compromised
    • Pain and discomfort addressed
  • Supervise child closely for 24 hours no driving for older children
  • Give advice leaflet to parents/carer
  • Ensure that sedation documented on EPR and drugs are signed for in CD book

Full trust policy is available on intranet here

Intranasal Fentanyl

There is was a national shortage of Intranasal Diamorphine therefore many departments are now more comfortable using Intranasal Fentanyl as a replacement for rapid provision of opioid analgesia in children.

  1. Intranasal (IN) fentanyl is a safe, non-invasive and effective analgesic for children with moderate to severe pain
  2. Fentanyl should be used in combination with non-pharmacological and other pharmacological pain management
  3. It can be used in conjunction with nitrous oxide for procedural sedation or prior to procedural sedation with ketamine

Dose is 1.5micrograms/Kg for the initial dose and 0.75micrograms/kg 10 minutes later if required.

Drug Delivery

Draw up the appropriate dose plus 0.1ml to allow for the dead space in the Mucosal Atomizer Device

Attach the MAD to the syringe

Sit the child at 45 degrees insert MAD loosely into the nostril and press the plunger

Doses greater than 0.5ml should be split between 2 nostrils

 

Contraindications

  • Blocked nose due to upper respiratory illness or epistaxis
  • Respiratory depression
  •  Hypovolaemia
  • Altered consciousness
  • Hypersensitivity to fentanyl
  •  Children below 1 year old

Full Intranasal Fentanyl SOP

Primary Intracerebral Haemorrhage

In anybody who there is suspicion of a non-traumatic haemorrhage arrange an urgent CT Head.

All patients need IV access and  U&E, FBC, Coag

If CT confirms PICH (not traumatic, not SAH): –

Anticoagulation

If anticoagulated with warfarin or NOAC discuss with stroke consultant and Haematologist regarding reversal

If not anticoagulated give Tranexamic acid – 1g in 100mls Saline/Glucose over 10 mins followed by 1g in 250mls Saline over 6 hours.

Blood Pressure

BP needs to be <150/80 – use labetalol (max 400mg – until BP <160 or HR <50) and GTN infusion

Neurosurgical Referral

Not all patients with intracerebral bleeds need referral to neurosurgery – you could save yourself and your patient a lot of time and effort!

Those to refer:

  • GCS 9-12/15 with lobar haemorrhage
  • Isolated intraventricual haemorrhage
  • Hydrocephalus on presentation
  • Rapid deterioration following arrival (gcs drop by 2 points or more in the motor component)
  • Cerebellar bleed

Admit those not going to Neurosurgery to HASU at CRH after discussion with Stroke team

Head Injury

Background

  • Defined as any traumatic injury to the head other than superficial facial injuries.
  • The commonest cause of death and disability in people age 1-40 in the UK.
  • Account for 1.4 million ED attendances each year, 95% of these are minor head injuries that can be managed in the ED.

Read more

Concealed Illicit Drugs

Background

Those suspected of concealing illicit drugs often present near ports and borders however they can present to any ED or be brought in by the police.

Body Packers – Swallow large quantities of well packaged drugs to smuggle them into countries or institutions.  These are often well manufactured with a low risk of rupture but the potential for serious toxicity if rupture occurs.

Body Stuffers – Swallow small quantities of poorly packaged illicit substances often at the point of arrest to conceal them. These have a much high risk of package rupture but involve smaller quantities of substances.

 

Investigations

Authorisation for an intimate search or radiological investigation must come from an inspector or higher with written consent from the patient.

Intimate searches must be carried out by a police surgeon but require immediately available resuscitation facilities therefore may be conducted in the ED. ED physicians should not handle the drugs at any time.

AXR or low dose CT scanning can be used to detect concealed packages in Body Packers.

 

General Management

Try to obtain a history of what and how much has been concealed

Look for toxidromes suggestive of package leak – treat as per Toxbase

  • Cocaine: Tachycardia, hypertension, agitation, diaphoresis, dilated pupils, hyperpyrexia, seizures, chest pain, arrhythmias and paranoia.
  • Heroin: pinpoint pupils, respiratory depression, decreased mental state, decreased bowel sounds
  • Amphetamines : – Nausea, Vomiting, Dilated Pupils, Tachycardia, Hypertensions, Sweating, Convulsions and the development of non-cardiogenic pulmonary oedema

 

Toxicology screens (urinary/blood) should not be used to guide management or discharge decisions (Level 5 evidence).

 

Body Stuffers & Pushers should be observed for signs of toxicity for a minimum 8 hours, consider activated Charcoal

Body Packers with positive imaging who are asymptomatic can be discharged back to police custody for monitoring. Bowel preparation such as Cleanprep or movicol can be used.

 

Body Packers with signs of cocaine or amphetamine toxicity or signs of obstruction/ileus require urgent surgical intervention.

Body packers with signs of Heroin toxicity should be treated with Naloxone infusion as per toxbase guidelines

All patients transferred to police custody should receive a discharge letter, including
Suspected Internal Drug Traffickers.

 

Algorithms

 

 

 

Full RCEM Guide

Hypertensive Disorders in Pregnancy

  • New onset hypertension after 20 weeks of gestation (systolic blood pressure > 140 and/or diastolic blood pressure > 90)

And either

  • Proteinuria (urine protein:creatinine ratio ≥30mg/mmol)

Or

  • Other features of pre-eclampsia1:
    • AKI (creatinine ≥ 90)
    • Liver dysfunction (ALT>40)/epigastric/RUQ pain
    • New severe persistent headache without an alternative diagnosis
    • Persistent visual disturbance
    • Haematological complications (platelets <150/DIC/haemolysis)
    • Neurological complications (clonus/stroke/seizures(eclampsia))
    • Pulmonary oedema
    • Uteroplacental dysfunction (fetal growth restriction/placental abruption/intrauterine death)

Onset is usually after 20 weeks of gestation, but it can also occur up to a few weeks postpartum.

Eclampsia- This is pre-eclampsia that has progressed to seizures

Risk Factors:

Clinical features of pre-eclampsia:

  • Asymptomatic hypertension (picked up on screening or incidentally when presenting with another issue)
  • Headache (usually frontal)
  • RUQ or epigastric pain (also a symptom of HELLP syndrome)
  • Nausea and vomiting
  • Oedema (common but not specific). Especially if rapidly increasing and involving face and hands.
  • Visual disturbance (flashing lights in the visual fields or scotomata)
  • Shortness of breath (uncommon but can occur due to pulmonary oedema)
  • Hyper-reflexia and/or clonus

HELLP syndrome is a variant of severe pre-eclampsia characterised by haemolysis, elevated liver enzymes and low platelets.4

Symptoms and signs are similar to those of pre-eclampsia but also include jaundice and bleeding.

Management of Pre-eclampsia:

 

  • Contact obstetrics early
  • Manage the patient in an area with close monitoring if pre-eclampsia with severe features
  • BP management:
    • Labetalol first line unless unsuitable or contraindicated3 (e.g. asthma)
    • Nifedipine MR second line
    • Methyldopa third line (not used postpartum due to risk of depression)
  • Careful fluid balance monitoring
    • Fluid restriction to reduce the risk of pulmonary oedema
    • Monitor urine output if severe
  • Consider IV magnesium sulphate for eclampsia prophylaxis if severe features of pre-eclampsia

Definitive management:

Definitive management of pre-eclampsia is ultimately delivery of the fetus.   Timing of delivery will be decided by senior members of the obstetric team according to the severity of pre-eclampsia, the current gestation and in consultation with the patient. Following diagnosis of pre-eclampsia, the majority of women are managed as inpatients until delivery.

 

ED Management of Eclampsia:

  • Ask for help early from ITU and obstetric teams
  • ABC approach, manage in left lateral position
  • Airway and breathing assessment with high flow oxygen
  • If inadequate ventilation, consider early intubation (laryngeal oedema in pre-eclampsia and increased risk of aspiration in pregnancy)
  • Magnesium sulphate IV is treatment of choice for seizures – 4g loading dose over 5-10 mins then 1g/hr infusion for 24 hours
  • Further 2g boluses of magnesium sulphate can be given if further seizures occur after initial loading.3
  • Patients will need to be managed in HDU/ITU to stabilise blood pressure prior to delivery

Full NICE guidance is available here

Opioid Toxicity

Opioid Toxicity causes:

  1. Drowsiness
  2. Respiratory Depression – Hypo-ventilation and decreased respiratory rate
  3. Pupillary Miosis

Other Symptoms may include (but are not diagnostic or opioid toxicity):

  • Nausea and vomiting
  •  Neuropsychiatric features including nightmares, anxiety, agitation, euphoria, dysphoria,
    depression, paranoia and hallucinations
  •  Urticaria and pruritis
  •  Convulsions
  •  Hypotension and bradycardia
  •  Hypothermia secondary to environmental exposure

Naloxone is the antidote to Opioids however as these are commonly co-ingested with other depressants. full reversal of symptoms may not occur with treatment.

In acute opioid toxicity, the aim of naloxone administration should be reversal of respiratory depression and maintenance of airway protective reflexes, not full reversal of unconsciousness.

 

Opioid Toxicity Treatment

Naloxone infusion if required is based on the total dose given to obtain Respiratory rate of 10

Link to the full guidance is here